Phenobarbital-induced Gingival Hyperplasia
ثبت نشده
چکیده
منابع مشابه
PharmGKB summary: phenytoin pathway.
Phenytoin is one of the most widely prescribed antiepileptic drugs (AEDs) in the USA (approximately 52% of AED prescriptions compared with 19% for valproic acid, 11% carbamazepine, and 7% phenobarbital) [1]. It has a narrow therapeutic range and wide interindividual variability in clearance and, as such, therapeutic drug monitoring is often necessary. Adverse effects of phenytoin range from min...
متن کاملThe effects of antiepileptic drugs on oral health.
OBJECTIVE Long-term use of phenytoin (PHT) causes gingival hyperplasia; however, little is known about the oral side effects of other antiepileptic drugs (AEDs). Through a systematic review of the literature, we explored the effects of AEDs on the oral health of patients with epilepsy. METHODS We searched PubMed, EMBASE and the Cochrane library between January 1963 and August 2010. The search...
متن کاملDrug-Induced Gingival Hyperplasia
This article has summarized observations and results of controlled laboratory and clinical studies of drug-induced gingival hyperplasia associated with phenytoin, cyclosporine, and nifedipine use. Furthermore, information regarding the pharmacologic aspects of these medications is presented. More information is needed for a greater understanding of drug-induced gingival hyperplasia. It appears ...
متن کاملDrug-induced gingival hyperplasia: a retrospective study using spontaneous reporting system databases
BACKGROUND Drug-induced gingival hyperplasia (DIGH) causes problems with chewing, aesthetics, and pronunciation, and leads to the deterioration of the patient's quality of life (QOL). Thus, the aim of this study was to evaluate the incidence of DIGH using spontaneous reporting system (SRS) databases. METHODS We analyzed reports of DIGH from SRS databases and calculated the reporting odds rati...
متن کاملAmlodipine Induced Gingival Hyperplasia
Amlodipine is a calcium channel blocker. Because of its long acting effect it is being widely used as antihypertensive drug. Gingival hyperplasia is one of its side effects. The histological and clinical evidences were consistent with amlodipine-induced gingival hyperplasia. The aim of publishing this report is to draw the attention of dentists towards this adverse effect.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2007